Article
Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.
The Journal of biological chemistry - 15 Nov 2013
Åhsberg Josefine, Ungerbäck Jonas, Strid Tobias, Welinder Eva, Stjernberg Jenny, Larsson Malin, Qian Hong, Sigvardsson Mikael
Abstract excerpt
Transcription factor doses are of importance for normal and malignant B-lymphocyte development; however, the understanding of underlying mechanisms and functional consequences of reduced transcription factor levels is limited. We have analyzed progenitor and B-lineage compartments in mice carryin...
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