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Article

The basic helix-loop-helix transcription factor E2-2 is involved in T lymphocyte development.

European journal of immunology - 1 Oct 2000

Bergqvist I, Eriksson M, Saarikettu J, Eriksson B, Corneliussen B, Grundström T, Holmberg D

Abstract excerpt

E2A, HEB and E2-2 genes encode a group of basic helix-loop-helix (bHLH) transcription factors that are structurally and functionally similar. Deletion of the genes encoding either of these proteins leads to early lethality and a block in B lymphocyte development. Evidence for a function in T lymp...

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Source

Identifiers

PMID: 11069067
DOI: 10.1002/1521-4141(200010)30:10<2857::AID-IMMU2857>3.0.CO;2-G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11069067-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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