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Article

Presence of activated ras correlates with increased cysteine proteinase activities in human colorectal carcinomas.

International journal of cancer - 21 Aug 1998

Kim K, Cai J, Shuja S, Kuo T, Murnane M J

Abstract excerpt

The metastatic potential of ras-transfected cells has been attributed in part to significant ras induction of proteinase expression. To determine whether primary cancers also demonstrate higher cysteine proteinase activities in the presence of activated ras genes or altered ras protein expression...

Topics

Blotting, Western
Carcinoma
Cathepsin B
Cathepsin L
Cathepsins
Colorectal Neoplasms
Cysteine Endopeptidases
Endopeptidases
Genes, ras
Humans
Mutation
ras Proteins

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Source

Identifiers

PMID: 9699522
DOI: 10.1002/(sici)1097-0215(19980821)79:4<324::aid-ijc4>3.0.co;2-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9699522-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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