Article
Differential expression of matrix metalloproteinases in activated c-ras-Ha-transfected immortalized human keratinocytes.
British journal of cancer - 1 Mar 1998
Meade-Tollin L C, Boukamp P, Fusenig N E, Bowen C P, Tsang T C, Bowden G T
Abstract excerpt
Elevated expression of matrix metalloproteinases (MMPs), a family of secreted proteinases that degrade matrix components of basement membranes and connective tissues, is strongly correlated with malignant expression in various human epithelial cancers and epithelial cancer cell lines. We have tested whether elevated levels of MMP expression are also associated with malignant progression in human cutaneous...
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