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Article

Cathepsins D, B, and L in transformed human breast epithelial cells.

Breast cancer research and treatment - 1 Jan 1996

Lah T T, Calaf G, Kalman E, Shinde B G, Somers R, Estrada S, Salero E, Russo J, Daskal I

Abstract excerpt

To investigate the regulation of lysosomal enzymes during carcinogenesis, we measured cathepsins (Cats) D, B, and L in MCF-10F, which is a human breast epithelial cell line, and cells evolved after treatment with carcinogen and transfected with c-Ha-ras oncogene. The clones used in this study, MCF-10FTras, D3, D3-1, and D3-1Tras, expressed no estrogen receptors and gradually increased invasive potential, while...

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Identifiers

PMID: 8872331
DOI: 10.1007/BF01806189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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