Article
Cathepsins D, B, and L in transformed human breast epithelial cells.
Breast cancer research and treatment - 1 Jan 1996
Lah T T, Calaf G, Kalman E, Shinde B G, Somers R, Estrada S, Salero E, Russo J, Daskal I
Abstract excerpt
To investigate the regulation of lysosomal enzymes during carcinogenesis, we measured cathepsins (Cats) D, B, and L in MCF-10F, which is a human breast epithelial cell line, and cells evolved after treatment with carcinogen and transfected with c-Ha-ras oncogene. The clones used in this study, MC...
Topics
- Breast
- Cathepsins
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Clone Cells
- Epithelial Cells
- Epithelium
- Female
- Humans
- Immunohistochemistry
- Phenotype
- Transfection