Article
ras mutation and expression of the ras-regulated genes osteopontin and cathepsin L in human esophageal cancer.
International journal of cancer - 4 Sept 1997
Casson A G, Wilson S M, McCart J A, O'Malley F P, Ozcelik H, Tsao M S, Chambers A F
Abstract excerpt
As part of our ongoing studies to characterize molecular alterations in a well-defined series of surgically resected esophageal cancers, we examined the expression of 2 ras-regulated genes, whose products (osteopontin and cathepsin L) previously were shown to be associated with tumor invasion and metastasis. RNA was extracted from primary esophageal tumors (adenocarcinomas, 19; squamous-cell carcinomas, 6) and...
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