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Article

Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma.

Journal of endocrinological investigation - 1 Jun 1998

Chiefari E, Russo D, Giuffrida D, Zampa G A, Meringolo D, Arturi F, Chiodini I, Bianchi D, Attard M, Trischitta V, Bruno R, Giannasio P, Pontecorvi A, Filetti S

Abstract excerpt

Medullary thyroid carcinoma (MTC) may occur either as a sporadic or familial (FMTC) disease. Multiple endocrine neoplasia (MEN) type 2, inherited as an autosomal dominant disease, is characterized by coexistence of MTC with other endocrine neoplasia. Activating mutations of the RET proto-oncogene, involving the somatic or the germinal cell lineage, are found in both inherited and acquired forms. In this study,...

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PMID: 9699127
DOI: 10.1007/BF03350771

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma.PMID 9699127Read ↗

Germline and somatic mutations of the RET proto-oncogene in apparently sporadic medullary thyroid carcinomas.Semantic proximity Read ↗

Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTC:s.Semantic proximity Read ↗

Mutation analysis of the RET proto-oncogene in Dutch families with MEN 2A, MEN 2B and FMTC: two novel mutations and one de novo mutation for MEN 2A.Semantic proximity Read ↗

RET protooncogene mutations in patients with apparently sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Low frequency of germline mutations in the RET proto‐oncogene in patients with apparently sporadic medullary thyroid carcinomaSemantic proximity Read ↗

RET proto-oncogene mutations in multiple endocrine neoplasia type 2 and medullary thyroid carcinoma.Semantic proximity Read ↗

Analysis of inherited genetic variants in ret proto-oncogene of Brazilian patients with apparently sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Mutational spectrum of multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma in taiwan.Semantic proximity Read ↗

RET proto-oncogene mutations are restricted to codon 634 and 618 in Korean families with multiple endocrine neoplasia 2A.Semantic proximity Read ↗

RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center.Semantic proximity Read ↗

RET proto-oncogene mutations in multiple endocrine neoplasia type 2 and medullary thyroid carcinoma.Semantic proximity Read ↗

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

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