Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTC:s.

doi:10.1093/hmg/3.8.1259

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTC:s.

Human molecular genetics - 1 Aug 1994

Zedenius J, Wallin G, Hamberger B, Nordenskjöld M, Weber G, Larsson C

Abstract excerpt

Since germline mutations in the RET proto-oncogene (RET) predisposing to tumor development in Familial Medullary Thyroid Carcinoma (FMTC), Multiple endocrine neoplasia type 2A (MEN 2A), and Multiple endocrine neoplasia type 2B (MEN 2B) were reported, it has become possible to identify gene carrie...

Topics

Adult
Aged
Base Sequence
Carcinoma, Medullary
Drosophila Proteins
Exons
Female
Genetic Testing
Humans
Male
Middle Aged
Molecular Sequence Data
Multiple Endocrine Neoplasia Type 2a
Mutation
Pedigree
Polymerase Chain Reaction
Proto-Oncogene Mas
Proto-Oncogene Proteins

Source

Open in PubMed

Identifiers

PMID: 7987299
DOI: 10.1093/hmg/3.8.1259

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7987299-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics