Article
RET protooncogene mutations in patients with apparently sporadic medullary thyroid carcinoma.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Aug 1998
Huang C N, Wu S L, Chang T C, Huang S H, Chang T J
Abstract excerpt
We examined RET protooncogene mutations in sporadic medullary thyroid carcinoma (MTC), using polymerase chain reaction (PCR)-based sequencing. DNA was extracted from tumor tissue and peripheral blood leukocytes of seven unrelated individuals with apparently sporadic MTC. Oligonucleotide primers were selected to amplify exons 10, 11, 13, 15, and 16 of the RET protooncogene, to examine the sequences of codons 609,...
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