Article
RET protooncogene mutations in patients with apparently sporadic medullary thyroid carcinoma.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Aug 1998
Huang C N, Wu S L, Chang T C, Huang S H, Chang T J
Abstract excerpt
We examined RET protooncogene mutations in sporadic medullary thyroid carcinoma (MTC), using polymerase chain reaction (PCR)-based sequencing. DNA was extracted from tumor tissue and peripheral blood leukocytes of seven unrelated individuals with apparently sporadic MTC. Oligonucleotide primers w...
Topics
- Adult
- Carcinoma, Medullary
- Drosophila Proteins
- Female
- Humans
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ret
- Proto-Oncogenes
- Receptor Protein-Tyrosine Kinases
- Thyroid Neoplasms
