Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA analysis of Duffy genes in American blacks.

Vox sanguinis - 1 Jan 1998

Moulds J M, Hayes S, Wells T D

Abstract excerpt

BACKGROUND: Because limited studies have shown that the Duffy genotype is not accurately reflected by the erythrocyte phenotype, we used PCR-RFLP to determine the true FY1 and FY2 gene frequencies in blacks. METHODS: Genomic DNA was extracted from 81 randomly selected black individuals, amplified using PCR, digested with BanI and electrophoresed in 1.8% gels. Direct DNA sequencing of the FY regulatory region was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Heterozygote
Share to Black People

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homozygote

Share to Phenotype

Share to Polymerase Chain Reaction

Share to United States

Source

Identifiers

PMID: 9691406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA analysis of Duffy genes in American blacks.PMID 9691406Read ↗

Molecular mechanisms that lead to reduced expression of duffy antigens.Semantic proximity Read ↗

The coding sequence of Duffy blood group gene in humans and simians: restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals.Semantic proximity Read ↗

A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele-specific primers.Semantic proximity Read ↗

The Fy(x) phenotype is associated with a missense mutation in the Fy(b) allele predicting Arg89Cys in the Duffy glycoprotein.Semantic proximity Read ↗

Arg89Cys substitution results in very low membrane expression of the Duffy antigen/receptor for chemokines in Fy(x) individuals.Semantic proximity Read ↗

A novel mutation in the coding sequence of the FY*B allele of the Duffy chemokine receptor gene is associated with an altered erythrocyte phenotype.Semantic proximity Read ↗

New genotypes in Fy(a-b-) individuals: nonsense mutations (Trp to stop) in the coding sequence of either FY A or FY B.Semantic proximity Read ↗

A novel FY allele in Brazilians.Semantic proximity Read ↗

The Duffy blood group system: a review.Semantic proximity Read ↗

Mutations in the erythrocyte chemokine receptor (Duffy) gene: the molecular basis of the Fya/Fyb antigens and identification of a deletion in the Duffy gene of an apparently healthy individual with the Fy(a-b-) phenotype.Semantic proximity Read ↗

The Duffy blood group system in the Tunisian population.Semantic proximity Read ↗

A novel FY*A allele with the 265T and 298A SNPs formerly associated exclusively with the FY*B allele and weak Fy(b) antigen expression: implication for genotyping interpretative algorithms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.