A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele-specific primers.

doi:10.1046/j.1537-2995.1998.38298193099.x

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Article

A clinically applicable method for determining the three major alleles at the Duffy (FY) blood group locus using polymerase chain reaction with allele-specific primers.

Transfusion - 1 Feb 1998

Olsson M L, Hansson C, Avent N D, Akesson I E, Green C A, Daniels G L

Abstract excerpt

BACKGROUND: The clinically significant antigens of the Duffy (Fy [FY]) blood group system are expressed on the red cell form of the FY glycoprotein, a promiscuous chemokine receptor and also a receptor for malarial parasites. After the cloning of cDNA coding for FY glycoprotein, the molecular bas...

Topics

Alleles
Blood Donors
DNA Primers
Duffy Blood-Group System
Humans
Polymerase Chain Reaction

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