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Article

New genotypes in Fy(a-b-) individuals: nonsense mutations (Trp to stop) in the coding sequence of either FY A or FY B.

British journal of haematology - 1 Feb 2000

Rios M, Chaudhuri A, Mallinson G, Sausais L, Gomensoro-Garcia A E, Hannon J, Rosenberger S, Poole J, Burgess G, Pogo O, Reid M

Abstract excerpt

Duffy blood group antigens are carried on a glycoprotein that is predicted to pass through the erythrocyte membrane seven times and is a promiscuous chemokine receptor. The Fy(a- b-) phenotype is present in two-thirds of African-American Blacks but is rare in Caucasians. In Blacks, the phenotype is due to a non-functional GATA-1 motif in the FY B, which silences the gene in erythrocytes but not in other tissues,...

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Identifiers

PMID: 10691880
DOI: 10.1046/j.1365-2141.2000.01882.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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New genotypes in Fy(a-b-) individuals: nonsense mutations (Trp to stop) in the coding sequence of either FY A or FY B.PMID 10691880Read ↗

Mutations in the erythrocyte chemokine receptor (Duffy) gene: the molecular basis of the Fya/Fyb antigens and identification of a deletion in the Duffy gene of an apparently healthy individual with the Fy(a-b-) phenotype.Semantic proximity Read ↗

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FY*A silencing by the GATA-motif variant FY*A(-69C) in a Caucasian family.Semantic proximity Read ↗

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