Article
The coding sequence of Duffy blood group gene in humans and simians: restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals.
Blood - 1 Feb 1995
Chaudhuri A, Polyakova J, Zbrzezna V, Pogo A O
Abstract excerpt
The coding and untranslated flanking sequences of Duffy gene (FY) in humans and simians are in a single exon. The difference between the two codominant alleles, FY*A and FY*B, is a single change at nucleotide 306: guanidine is in FY*A and adenine is in FY*B. This produces a codon change that subsequently modifies the amino acid at position 43 of gpFy, the major subunit of the Duffy blood group protein complex....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.