Phenotypic effects of the forced expression of HNF4 and HNF1alpha are conditioned by properties of the recipient cell.

doi:10.1242/jcs.111.16.2411

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Article

Phenotypic effects of the forced expression of HNF4 and HNF1alpha are conditioned by properties of the recipient cell.

Journal of cell science - 1 Aug 1998

Bailly A, Späth G, Bender V, Weiss M C

Abstract excerpt

Tagged versions of HNF4 or HNF1alpha cDNAs in expression vectors have been introduced by transient and stable transfection into three cell lines of hepatic origin that all fail to express these two liver-enriched transcription factors and hepatic functions. C2 and H5 cells are dedifferentiated ra...

Topics

Animals
Base Sequence
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Cell Differentiation
Cell Line
Chromosomes, Human, Pair 2
DNA-Binding Proteins
Gene Expression
Hepatocyte Nuclear Factor 1
Hepatocyte Nuclear Factor 1-alpha
Hepatocyte Nuclear Factor 1-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatocyte Nuclear Factor 4

Humans

Hybrid Cells

Liver

Liver Neoplasms, Experimental

Nuclear Proteins

Oligonucleotide Probes

Source

Open in PubMed

Identifiers

PMID: 9683635
DOI: 10.1242/jcs.111.16.2411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9683635-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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