Cell phenotype, binding affinity and promoter structure modulate transactivation by HNF1 and LAP.

doi:10.1242/jcs.103.4.1083

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Article

Cell phenotype, binding affinity and promoter structure modulate transactivation by HNF1 and LAP.

Journal of cell science - 1 Dec 1992

Angrand P O, Rousset J P, Weiss M C

Abstract excerpt

To evaluate the importance of the transcription factors known to bind to the albumin promoter as well as the parameters involved in their activity, we have used cotransfections with an albumin promoter-cat plasmid combined with expression vectors driving the expression of cDNAs coding for liver-enriched factors known to interact with this promoter. We describe the characteristics of a set of clones of hepatic...

Topics

Albumins
Binding Sites
CCAAT-Enhancer-Binding Proteins
Cell Line
DNA-Binding Proteins
Gene Expression Regulation
Hepatocyte Nuclear Factor 1
Hepatocyte Nuclear Factor 1-beta
Liver
Nuclear Proteins
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Protein Binding

Recombinant Fusion Proteins

Transcription Factors

Transcriptional Activation

Transfection

Source

Open in PubMed

Identifiers

PMID: 1487491
DOI: 10.1242/jcs.103.4.1083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1487491-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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