Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types.

Nucleic acids research - 15 Jan 1998

Nakhei H, Lingott A, Lemm I, Ryffel G U

Abstract excerpt

The transcription factor hepatocyte nuclear factor 4alpha (HNF4alpha) is a tissue specific transcription factor mainly expressed in the liver, kidney, intestine and the endocrine pancreas, but is also an essential regulator for early embryonic events. Based on its protein structure HNF4alpha is classified as an orphan member of the nuclear receptor superfamily. Comparing HNF4alpha transcription factors in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genetic Variation

Share to Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 9421506
DOI: 10.1093/nar/26.2.497
PMCID: PMC147295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types.PMID 9421506Read ↗

Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing.Semantic proximity Read ↗

Human Hepatocyte Nuclear Factor 4 Isoforms Are Encoded by Distinct and Differentially Expressed GenesSemantic proximity Read ↗

Human Hepatocyte Nuclear Factor 4-α Encodes Isoforms with Distinct Transcriptional FunctionsSemantic proximity Read ↗

More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing.Semantic proximity Read ↗

Human Hepatocyte Nuclear Factor 4-α encodes isoforms with distinct transcriptional functionsSemantic proximity Read ↗

Novel P2 promoter-derived HNF4alpha isoforms with different N-terminus generated by alternate exon insertion.Semantic proximity Read ↗

Two members of an HNF1 homeoprotein family are expressed in human liverSemantic proximity Read ↗

HNF4α in Hepatocyte Health and DiseaseSemantic proximity Read ↗

Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification.Semantic proximity Read ↗

The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.Semantic proximity Read ↗

The impact of hepatocyte nuclear factor-1α on liver malignancies and cell stemness with metabolic consequences.Semantic proximity Read ↗

Identification of target genes of the transcription factor HNF1β and HNF1α in a human embryonic kidney cell lineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.