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Article

Single gene complementation of the hPMS2 defect in HEC-1-A endometrial carcinoma cells.

Cancer research - 15 Jul 1998

Risinger J I, Umar A, Glaab W E, Tindall K R, Kunkel T A, Barrett J C

Abstract excerpt

Results from the analysis of human tumor cell lines with mutations in DNA mismatch repair genes have contributed to the understanding of the functions of these gene products in DNA mismatch repair, microsatellite instability, cell cycle checkpoint control, transcription-coupled nucleotide excision repair, and resistance to cytotoxic agents. However, complementation of human DNA mismatch repair defects by...

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Source

Identifiers

PMID: 9679958

Genes

PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Single gene complementation of the hPMS2 defect in HEC-1-A endometrial carcinoma cells.PMID 9679958Read ↗

A hPMS2 mutant cell line is defective in strand-specific mismatch repair.Semantic proximity Read ↗

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The human MLH1 cDNA complements DNA mismatch repair defects in Mlh1-deficient mouse embryonic fibroblasts.Semantic proximity Read ↗

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Complementation of mismatch repair gene defects by chromosome transfer.Semantic proximity Read ↗

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.Semantic proximity Read ↗

Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance.Semantic proximity Read ↗

Evidence for Involvement of HMGB1 Protein in Human DNA Mismatch RepairSemantic proximity Read ↗

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor αSemantic proximity Read ↗

A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.Semantic proximity Read ↗

Mutation spectrum of MSH3-deficient HHUA/chr.2 cells reflects in vivo activity of the MSH3 gene product in mismatch repair.Semantic proximity Read ↗

Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes.Semantic proximity Read ↗

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