Article
Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
DNA repair - 1 Feb 2008
Hazrati Ali, Ramis-Castelltort Marc, Sarkar Sovan, Barber Louise J, Schofield Christopher J, Hartley John A, McHugh Peter J
Abstract excerpt
Pso2/Snm1 plays a key role in the repair of DNA interstrand cross-links in yeast. Human cells possess three orthologues of Pso2; SNM1A, SNM1B/Apollo and SNM1C/Artemis. Studies using mammalian cells disrupted or depleted for these genes have yielded equivocal evidence that any of these is a true f...
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