Article
HLA haplotype sharing in rheumatoid arthritis sibships: risk estimates subdivided by proband genotype.
Genetic epidemiology - 1 Jan 1998
Rigby A S, MacGregor A J, Thomson G
Abstract excerpt
There is a well-known association between rheumatoid arthritis (RA) and HLA-DR4. Recent research has indicated that both DR4 haplotypes are important in disease predisposition (favoring a recessive mode of inheritance). Others have suggested that certain combinations of genotypes, in particular Dw4/Dw14 heterozygotes, may be more important than others. We examined the mode of inheritance of RA using data from the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
