Article
Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes.
Springer seminars in immunopathology - 1 Jan 1998
Weyand C M, Klimiuk P A, Goronzy J J
Abstract excerpt
Rheumatoid arthritis (RA) is now recognized as a multigene disorder with a number of genetic polymorphisms contributing to disease pathogenesis. Here, we propose that the diagnostic category of RA includes multiple subtypes of disease and that the different phenotypes of RA correlate to different genotypes. Support for this concept has come from a reappraisal of the clinical heterogeneity of RA and the...
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