Article
Both inherited HLA-haplotypes are important in the predisposition to rheumatoid arthritis.
British journal of rheumatology - 1 Oct 1993
Deighton C M, Cavanagh G, Rigby A S, Lloyd H L, Walker D J
Abstract excerpt
The distribution of the HLA-DR allele frequencies of 105 RA patients has been compared with the expected distribution under recessive and dominant modes of inheritance using control data from 2041 controls and the antigen genotype frequency among patients methodology. The observed distribution was compatible with a recessive mode of HLA-linked inheritance in RA, with a dominant mode rejected, whether HLA-DR4 was...
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