Article
Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis.
American journal of human genetics - 1 Feb 1996
Meyer J M, Han J, Singh R, Moxley G
Abstract excerpt
The association between rheumatoid arthritis (RA) and HLA DRB1 alleles may arise through linkage disequilibrium with a disease locus or the direct involvement of HLA alleles in RA. In support of the latter possibility, the shared-epitope hypothesis has been postulated, stating that conformational...
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