Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA haplotypes in a family with multiple cases of rheumatoid arthritis.

The Journal of rheumatology - 1 Jan 2000

Michalski J P, McCombs C C, DeJesus I B, Anderson J L

Abstract excerpt

Population studies have identified the histocompatibility antigen HLA-DR4 to be a genetic marker of significantly increased risk for the development of rheumatoid arthritis (RA). Family studies are now beginning to elucidate the role of this and other genetic factors in the pathogenesis of RA. We...

Topics

Adult
Arthritis, Rheumatoid
Female
Genes, MHC Class II
Genotype
HLA-DR4 Antigen
Histocompatibility Antigens Class II
Humans
Lymphocyte Culture Test, Mixed
Male
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 6214630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-6214630-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA haplotypes in a family with multiple cases of rheumatoid arthritis.PMID 6214630Read ↗

HLA typing in a large family with multiple cases of different autoimmune diseases.Semantic proximity Read ↗

HLA haplotype sharing in rheumatoid arthritis sibships: risk estimates subdivided by proband genotype.Semantic proximity Read ↗

Both inherited HLA-haplotypes are important in the predisposition to rheumatoid arthritis.Semantic proximity Read ↗

The genetic contribution to the pathogenesis of rheumatoid arthritis.Semantic proximity Read ↗

Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis.Semantic proximity Read ↗

HLA-linked rheumatoid arthritis.Semantic proximity Read ↗

Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men.Semantic proximity Read ↗

HLA-DRB1 genes in 5 rheumatic disease multi-case families.Semantic proximity Read ↗

HLA-DR genotypes in familial rheumatoid arthritis: increased frequency of protective and neutral alleles in a multicase family.Semantic proximity Read ↗

Immunogenetic differences between patients with familial and non-familial rheumatoid arthritis.Semantic proximity Read ↗

Prediction of susceptibility to rheumatoid arthritis by human leukocyte antigen genotyping.Semantic proximity Read ↗

Coexistence of rheumatoid arthritis in married couples: a search for etiological factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.