Article
The NA"null" phenotype of a young man is caused by an Fc gammaRIIIB gene deficiency while the products of the neighboring Fc gammaRIIA and Fc gammaRIIIA genes are present.
Annals of hematology - 1 May 1998
Flesch B K, Achtert G, Bauer F, Neppert J
Abstract excerpt
A 27-year-old man with an allergy to house dust mites was found to lack the Fc gammaRIIIb on his neutrophils. Cell surface marker and PCR techniques were used to investigate possible reasons for this deficiency. Agglutination and immunofluorescence assays using the man's neutrophils together with...
Topics
- Adult
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, CD19
- DNA
- Flow Cytometry
- Fluorescent Antibody Technique, Indirect
- Humans
- Isoantigens
- Male
- Monocytes
- Neutrophils
- Phagocytosis
- Phenotype
- Polymerase Chain Reaction
- Receptors, IgG