Article
Fc gamma receptor III on human neutrophils. Allelic variants have functionally distinct capacities.
The Journal of clinical investigation - 1 Apr 1990
Salmon J E, Edberg J C, Kimberly R P
Abstract excerpt
As a model system to explore the functional consequences of structural variants of human Fc gamma receptors (Fc gamma R), we have investigated Fc gamma R-mediated phagocytosis in relation to the NA1-NA2 polymorphism of Fc gamma RIII (CD16) on neutrophils (Fc gamma RIIIPMN). The neutrophil-specific NA antigen system is a biallelic polymorphism with codominant expression demonstrating a gene dose effect with the...
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