Article
The use of allele-specific recombinant Fc gamma receptor IIIb antigens for the detection of granulocyte antibodies.
Blood - 1 Jan 1999
Bux J, Kissel K, Hofmann C, Santoso S
Abstract excerpt
The Fcgamma receptor IIIb (FcgammaRIIIb) for the Fc domain of IgG is expressed exclusively on neutrophils. The FcgammaRIIIb bears allotypic polymorphisms referred to as NA1, NA2, and SH, which are known for their frequent involvement in alloimmune and autoimmune neutropenias as well as in transfu...
Topics
- Alleles
- Animals
- Antigens
- Autoantibodies
- CHO Cells
- Cell Line
- Cricetinae
- Gene Expression
- Genotype
- Granulocytes
- Humans
- Isoantibodies
- Polymerase Chain Reaction
- Precipitin Tests
- Receptors, IgG
- Recombinant Proteins
- Transfection