Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fcγ receptor IIIb (CD16b) polymorphisms are associated with susceptibility to idiopathic pulmonary fibrosis.

Lung - 1 Dec 2010

Bournazos Stylianos, Bournazou Irini, Murchison John T, Wallace William A, McFarlane Pauline, Hirani Nikhil, Simpson A John, Dransfield Ian, Hart Simon P

Abstract excerpt

An excess of neutrophils in the alveoli and lung interstitium has been described in idiopathic pulmonary fibrosis (IPF). Engagement of neutrophil Fcγ receptors with IgG complexes may contribute to the pathogenesis of IPF. The neutrophil FcγRIIIb receptor occurs in two codominantly expressed allelic variants, NA1 and NA2, which exhibit different binding affinities for IgG1 and IgG3 subclasses. The aim of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Forced Expiratory Volume

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GPI-Linked Proteins

Share to Idiopathic Pulmonary Fibrosis

Share to Receptors, IgG

Share to Scotland

Share to Vital Capacity

Source

Identifiers

PMID: 20924590
DOI: 10.1007/s00408-010-9262-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fcγ receptor IIIb (CD16b) polymorphisms are associated with susceptibility to idiopathic pulmonary fibrosis.PMID 20924590Read ↗

FcγRIIIb-deficient neutrophils have defects in ROS production, phagocytosis and actin polymerization following stimulation through FcγRsSemantic proximity Read ↗

FcgammaR polymorphisms: Implications for function, disease susceptibility and immunotherapy.Semantic proximity Read ↗

Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups.Semantic proximity Read ↗

Relevance of IgG receptor IIIb (CD16) polymorphism to handling of Porphyromonas gingivalis: implications for the pathogenesis of adult periodontitis.Semantic proximity Read ↗

Copy number variation of FCGR3B is associated with susceptibility to idiopathic pulmonary fibrosis.Semantic proximity Read ↗

FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.Semantic proximity Read ↗

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.Semantic proximity Read ↗

Allelic and copy-number variations of FcγRs affect granulocyte function and susceptibility for autoimmune blistering diseases.Semantic proximity Read ↗

Haplotypes of FcγRIIa and FcγRIIIb polymorphic variants influence IgG-mediated responses in neutrophils.Semantic proximity Read ↗

Variations in genes encoding neutrophil antigens NA1 and NA2.Semantic proximity Read ↗

Evaluation of Human FcγRIIA (CD32) and FcγRIIIB (CD16) Polymorphisms in Caucasians and African-Americans Using Salivary DNASemantic proximity Read ↗

Genotypical classification of neutrophil Fc gamma receptor III by polymerase chain reaction-single-strand conformation polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.