Article
Variations in genes encoding neutrophil antigens NA1 and NA2.
Transfusion - 1 Jun 2000
Matsuo K, Procter J, Stroncek D
Abstract excerpt
BACKGROUND: Neutrophil-specific antigens NA1 and NA2 are located on Fcgamma receptor IIIb (FcgammaRIIIb). NA1 and NA2 forms of FcgammaRIIIb differ by four amino acids and the corresponding genes by five nucleotides. Variations in NA gene frequencies are encountered among ethnic groups. Altered forms of the genes are expected among individuals. STUDY DESIGN AND METHODS: RFLPs associated with four recognition sites...
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