Neutrophil Fc gamma RIIIb deficiency, nature, and clinical consequences: a study of 21 individuals from 14 families.

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Article

Neutrophil Fc gamma RIIIb deficiency, nature, and clinical consequences: a study of 21 individuals from 14 families.

Blood - 15 Sept 1995

de Haas M, Kleijer M, van Zwieten R, Roos D, von dem Borne A E

Abstract excerpt

Several individuals have been described whose neutrophils lack the normally abundantly expressed IgG Fc gamma receptor IIIb (Fc gamma RIIIb). We now studied the responsible genomic defect and analyzed the medical history in detail of 21 Fc gamma RIIIb-negative donors identified in 14 unrelated fa...

Topics

Adolescent
Adult
Aged
Alleles
Base Sequence
Blotting, Southern
Disease Susceptibility
Female
Genes
Humans
Immunity, Maternally-Acquired
Infant, Newborn
Infections
Isoantibodies
Male
Middle Aged
Molecular Sequence Data
Neutropenia

Source

Open in PubMed

Identifiers

PMID: 7662988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7662988-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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