Article
Abnormal neutrophil phenotype and neutrophil FcRIII deficiency corrected by bone marrow transplantation.
Transfusion - 1 Oct 1995
Minchinton R M, de Haas M, von dem Borne A E, Kleijer M, Roberts A W, Gillett E A
Abstract excerpt
BACKGROUND: Neutrophils from a patient in first remission of acute myeloid leukemia were found to lack NA1 and NA2 alloantigens. This NA null phenotype was converted to the normal phenotype of NA1, NB2 by the transplantation of bone marrow from an HLA-identical sibling. To investigate the inherit...
Topics
- Adult
- Base Sequence
- Bone Marrow Transplantation
- DNA
- Female
- Genotype
- Hair
- Humans
- Leukemia, Myeloid, Acute
- Molecular Sequence Data
- Neutrophils
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, IgG