Apolipoprotein E epsilon 4 allele in association with global cognitive performance and CSF markers in Alzheimer's disease.

doi:10.1002/(sici)1099-1166(1998110)13:11<767::aid-gps866>3.0.co;2-f

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Article

Apolipoprotein E epsilon 4 allele in association with global cognitive performance and CSF markers in Alzheimer's disease.

International journal of geriatric psychiatry - 1 Nov 1998

Lasser R A, Dukoff R, Levy J, Levin R, Lehtimäki T, Seubert P, Sunderland T

Abstract excerpt

To better define the influence of apolipoprotein E (ApoE) epsilon 4 genotype on the cognitive and biochemical features of Alzheimer's disease (AD), cross-sectional analysis of global cognitive measures and cerebrospinal fluid studies gathered on AD subjects at a tertiary care facility between 1986 and 1997 was carried out. The 112 AD patients examined included 62 women and 50 men with a mean (SD) age of 64.2...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Cognition Disorders
Female
Gene Frequency
Genetic Markers
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Male

Middle Aged

Neuropsychological Tests

tau Proteins

Source

Open in PubMed

Identifiers

PMID: 9850873
DOI: 10.1002/(sici)1099-1166(1998110)13:11<767::aid-gps866>3.0.co;2-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9850873-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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