Article
Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.
Neurology - 1 Mar 1996
Myers R H, Schaefer E J, Wilson P W, D'Agostino R, Ordovas J M, Espino A, Au R, White R F, Knoefel J E, Cobb J L, McNulty K A, Beiser A, Wolf P A
Abstract excerpt
Apolipoprotein E type 4 allele (apoE epsilon4) is associated with Alzheimer's disease (AD) in the late-onset familial form and in sporadic cases, but the age-associated risk in a randomly sampled elderly population is not established. We examined the association of apoE epsilon4 with AD and other...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Base Sequence
- Cohort Studies
- Dementia
- Female
- Humans
- Incidence
- Longitudinal Studies
- Male
- Middle Aged