Article
Cellular phenotype transformation during early embryogenesis: a role for focal adhesion kinase?
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 1998
Ridyard M S, Sanders E J
Abstract excerpt
We have used the gastrulating chick embryo as a model for studying the potential role of focal adhesion kinase (FAK) in phenotypic transformation. In the gastrulating embryo, there is a well-defined epithelial to mesenchymal transformation as the upper epithelial epiblast layer of cells ingresses at the primitive streak to form the invasive mesenchymal mesoderm layer and the epithelioid endoderm layer....
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