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Article

FGF controls epithelial-mesenchymal transitions during gastrulation by regulating cell division and apicobasal polarity.

Development (Cambridge, England) - 1 Oct 2018

Sun Jingjing, Stathopoulos Angelike

Abstract excerpt

To support tissue and organ development, cells transition between epithelial and mesenchymal states. Here, we have investigated how mesoderm cells change state in Drosophila embryos and whether fibroblast growth factor (FGF) signaling plays a role. During gastrulation, presumptive mesoderm cells invaginate, undergo an epithelial-to-mesenchymal state transition (EMT) and migrate upon the ectoderm. Our data show...

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Identifiers

PMID: 30190277
DOI: 10.1242/dev.161927
PMCID: PMC6198468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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