Article
HIV-1-infected long-term slow progressors heterozygous for delta32-CCR5 show significantly lower plasma viral load than wild-type slow progressors.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Jul 1998
Walli R, Reinhart B, Luckow B, Lederer E, Loch O, Malo A, Wank R, Schlöndorff D, Goebel F D
Abstract excerpt
OBJECTIVE: Patients heterozygous for delta32-CCR5 may have a delayed progression of HIV-1 disease. The aim of the present study was to investigate the influence of CCR5/delta32-CCR5 genotype in long-term slow progressors using plasma viral load as a marker of disease progression. DESIGN: We analy...
Topics
- Cohort Studies
- Disease Progression
- Genotype
- HIV Infections
- HIV-1
- Heterozygote
- Humans
- Lymphocyte Count
- Lymphocyte Subsets
- Receptors, CCR5
- Viral Load
- Viremia
