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Article

CCR5 genotypes and progression to HIV disease in perinatally infected children.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Apr 2007

de Angelis Daniela Souza Araújo, Freire Wilton Santos, Pannuti Cláudio Sergio, Succi Regina Célia de Menezes, Machado Daisy Maria

Abstract excerpt

The CCR5 molecule, a chemokine receptor, is the most important co-receptor for macrophage-tropic HIV-1. A 32-bp deletion in the gene encoding CCR5 (CCR5-del32) confers nearly complete resistance to HIV-1 infection in homozygotes, and slows the rate of progression to AIDS in heterozygous adults. The aim of this study was to describe the CCR5 genotypes and the characteristics of HIV disease progression in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Electrophoresis, Agar Gel

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Source

Identifiers

PMID: 17625759
DOI: 10.1590/s1413-86702007000200004

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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