Article
Allelotype of 28 human breast cancer cell lines and xenografts.
British journal of cancer - 15 Dec 2003
Harkes I C, Elstrodt F, Dinjens W N M, Molier M, Klijn J G M, Berns E M J J, Schutte M
Abstract excerpt
Heterozygous loss of relatively large chromosomal regions is a hallmark of the inactivation of tumour suppressor genes. Searching for deletions in cancer genomes therefore provides an attractive option to identify new tumour suppressor genes. Here, we have performed a genome-wide survey for regions exhibiting allelic loss in 24 commercially available breast cancer cell lines and four breast cancer xenografts,...
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