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Article

A search for novel tumour suppressor genes for adult acute leukaemia by allelotyping at sub-telomeric chromosomal regions.

Mutation research - 25 May 1998

Giphart-Gassler M, De Nooij-Van Dalen A, Van Buuren-Van Seggelen V, Morolli B, Lohman P, Kluin-Nelemans H

Abstract excerpt

A search was initiated towards the localization of novel mutated tumour suppressor genes that may be involved in adult leukaemia. For this purpose, we measured the occurrence of loss of heterozygosity (LOH) in nine patients with acute B-lineage leukaemia (ALL) and one with undifferentiated leukaemia (AUL). Eight leukaemias exhibited a diploid karyotype. For each patient, PCR products of 130 polymorphic...

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Identifiers

PMID: 9685700
DOI: 10.1016/s0027-5107(98)00022-0

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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