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Article

A search for novel tumour suppressor genes for adult acute leukaemia by allelotyping at sub-telomeric chromosomal regions.

Mutation research - 25 May 1998

Giphart-Gassler M, De Nooij-Van Dalen A, Van Buuren-Van Seggelen V, Morolli B, Lohman P, Kluin-Nelemans H

Abstract excerpt

A search was initiated towards the localization of novel mutated tumour suppressor genes that may be involved in adult leukaemia. For this purpose, we measured the occurrence of loss of heterozygosity (LOH) in nine patients with acute B-lineage leukaemia (ALL) and one with undifferentiated leukae...

Topics

Adolescent
Adult
Aged
Alleles
Burkitt Lymphoma
Chromosome Mapping
Female
Genes, Tumor Suppressor
Homozygote
Humans
Loss of Heterozygosity
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Repeats

Mutation

Telomere

Source

Identifiers

PMID: 9685700
DOI: 10.1016/s0027-5107(98)00022-0

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9685700-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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