Article
Comprehensive allelotyping of hepatoblastoma.
Hepato-gastroenterology - 1 Jan 2000
Terada Yoshie, Matsumoto Satoshi, Bando Kouichi, Tajiri Takashi
Abstract excerpt
BACKGROUND/AIMS: Hepatoblastoma is the most common malignant liver tumor to affect young children. METHODOLOGY: To identify loci of potential tumor suppressor genes, associated with HB, we carried out a genome-wide allelotyping study in panel of 15 HBs using 67 highly polymorphic microsatellite markers including 14 known tumor suppressor gene loci. RESULTS: Allelic losses at microsatellite loci were frequent on...
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