Article
Expression of altered alpha2-adrenergic phenotypic traits in normotensive humans at genetic risk of hereditary (essential) hypertension.
Journal of hypertension - 1 Jun 1998
Dao T T, Kailasam M T, Parmer R J, Le H V, Le Verge R, Kennedy B P, Ziegler G, Insel P A, Wright F A, O'Connor D T
Abstract excerpt
BACKGROUND: Essential (hereditary) hypertension is a common, though complex, trait with substantial heritability, but a still-obscure mode of inheritance. In this disorder with relatively late onset, knowledge of phenotypes with earlier penetrance would aid genetic analyses, as well as assessment...
Topics
- Adolescent
- Adrenergic alpha-2 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adult
- Aged
- Blood Pressure
- Catecholamines
- Chromatography, High Pressure Liquid
- Chromogranin A
- Chromogranins
- Female
- Humans
- Hypertension
- Infusions, Intravenous