Article
The phenotypic patterns of essential hypertension are the key to identifying "high blood pressure" genes.
Physiological research - 1 Jan 2010
Korner P I
Abstract excerpt
The genes that cause or increase susceptibility to essential hypertension (EH) and related animal models remain unknown. Their identification is unlikely to be realized with current genetic approaches, because of ambiguities in the genotype-phenotype relationships in these polygenic disorders. In turn, the phenotype is not just an aggregate of traits, but needs to be related to specific components of the...
Topics
- Humans
- Hyperinsulinism
- Hypertension
- Obesity
- Phenotype
- Vasoconstriction