Developmental effect of polyamine depletion in Caenorhabditis elegans.

doi:10.1042/bj3330309

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Article

Developmental effect of polyamine depletion in Caenorhabditis elegans.

The Biochemical journal - 15 Jul 1998

MacRae M, Kramer D L, Coffino P

Abstract excerpt

Ornithine decarboxylase (ODC) catalyses the conversion of ornithine to putrescine, an obligate precursor to the polyamines spermidine and spermine. We reported previously that homozygous odc-1 (pc13) worms have no detectable ODC activity. Despite their inability to make polyamines, these mutant w...

Topics

Animals
Caenorhabditis elegans
Disorders of Sex Development
Fertility
Larva
Male
Mutation
Ornithine Decarboxylase
Polyamines

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