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Article

Developmental effect of polyamine depletion in Caenorhabditis elegans.

The Biochemical journal - 15 Jul 1998

MacRae M, Kramer D L, Coffino P

Abstract excerpt

Ornithine decarboxylase (ODC) catalyses the conversion of ornithine to putrescine, an obligate precursor to the polyamines spermidine and spermine. We reported previously that homozygous odc-1 (pc13) worms have no detectable ODC activity. Despite their inability to make polyamines, these mutant worms appear normal, but with a slight reduction in total brood size, when grown in complex medium that presumably...

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Identifiers

PMID: 9657970
DOI: 10.1042/bj3330309
PMCID: PMC1219587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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