Article
Neurospora mutants affecting polyamine-dependent processes and basic amino acid transport mutants resistant to the polyamine inhibitor, alpha-difluoromethylornithine.
Genetics - 1 Nov 1994
Davis R H, Lieu P, Ristow J L
Abstract excerpt
Polyamines (spermidine and spermine) are required by living cells, but their functions are poorly understood. Mutants of Neurospora crassa with enhanced or diminished sensitivity to interference with polyamine synthesis, originally selected to study the regulation of the pathway, were found to ha...
Topics
- Amino Acids
- Biological Transport
- Drug Resistance, Microbial
- Eflornithine
- Mutation
- Neurospora crassa
- Ornithine Decarboxylase
- Polyamines
- Selection, Genetic
