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Article

Vacuolating toxin production in clinical isolates of Helicobacter pylori with different vacA genotypes.

The Journal of infectious diseases - 1 Jul 1998

Wang H J, Kuo C H, Yeh A A, Chang P C, Wang W C

Abstract excerpt

A vacuolating cytotoxin encoded by vacA in Helicobacter pylori is known as a potential virulent determinant. The relationship between different vacA alleles, vacuolating ability, and H. pylori-related diseases was investigated. Genetic analysis of 119 isolates from Taiwanese patients revealed that 104 strains were s1a/m2, 13 strains were characterized as the s1a/m1T type, which was more homologous to the s1a/m1...

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Identifiers

PMID: 9652442
DOI: 10.1086/515600

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