Article
Vacuolating toxin production in clinical isolates of Helicobacter pylori with different vacA genotypes.
The Journal of infectious diseases - 1 Jul 1998
Wang H J, Kuo C H, Yeh A A, Chang P C, Wang W C
Abstract excerpt
A vacuolating cytotoxin encoded by vacA in Helicobacter pylori is known as a potential virulent determinant. The relationship between different vacA alleles, vacuolating ability, and H. pylori-related diseases was investigated. Genetic analysis of 119 isolates from Taiwanese patients revealed tha...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Cytotoxins
- DNA, Bacterial
- Dyspepsia
- Genotype
- HeLa Cells
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Molecular Sequence Data
- Peptic Ulcer
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Stomach Neoplasms