Article
Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China.
The Journal of infectious diseases - 1 Jul 1998
Pan Z J, Berg D E, van der Hulst R W, Su W W, Raudonikiene A, Xiao S D, Dankert J, Tytgat G N, van der Ende A
Abstract excerpt
Studies of Helicobacter pylori from the West have linked production of vacuolating cytotoxin and a particular signal sequence (s1a) allele of the underlying vacA gene to peptic ulcer disease (PUD). Among Chinese H. pylori, most isolates from both PUD and gastritis patients were toxigenic (35/46 a...
Topics
- Alleles
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- China
- Cytotoxins
- DNA, Bacterial
- Gastritis
- HeLa Cells
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Molecular Sequence Data
- Peptic Ulcer
- Phenotype