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Article

Relationship of <i>vacA</i> Genotypes of <i>Helicobacter pylori</i> to <i>cagA</i> Status, Cytotoxin Production, and Clinical Outcome

1 Dec 1998

Abstract excerpt

BACKGROUND: Mosaicism in vacA alleles with three distinct families of vacA signal sequences (s1a, s1b and s2) and two distinct families of middle region alleles (m1 and m2) has been reported. It was suggested that the vacA s1a genotype was closely associated with duodenal ulcer disease and with high cytotoxin production. The aim of this study was to evaluate the role of vacA genotyping with respect to gastric...

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Identifiers

PMID: 9844065
DOI: 10.1046/j.1523-5378.1998.08056.x

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