Article
Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases.
Journal of clinical microbiology - 1 Apr 1998
Rudi J, Kolb C, Maiwald M, Kuck D, Sieg A, Galle P R, Stremmel W
Abstract excerpt
The vacuolating cytotoxin and the cytotoxin-associated protein, encoded by vacA and cagA, respectively, are important virulence determinants of Helicobacter pylori. Sixty-five H. pylori strains were isolated from dyspeptic patients (19 with peptic ulcer disease, 43 with chronic gastritis, and 3 w...
Topics
- Antigens, Bacterial
- Bacterial Proteins
- Cytotoxins
- Genes, Bacterial
- Genotype
- HeLa Cells
- Helicobacter pylori
- Humans
