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Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview

16 Oct 2018

Abstract excerpt

BACKGROUND: Helicobacter pylori, gastric cancer-causing bacteria, survive in their gastric environment of more than 50% of the world population. The presence of H. pylori in the gastric vicinity promotes the development of various diseases including peptic ulcer and gastric carcinoma. H. pylori produce and secret Vacuolating cytotoxin A (VacA), a major toxin facilitating the bacteria against the host defense...

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PMID: 30324717
DOI: 10.1111/hel.12544

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