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Article

RecA protein of Escherichia coli has a third essential role in SOS mutator activity.

Journal of bacteriology - 1 Jun 1990

Sweasy J B, Witkin E M, Sinha N, Roegner-Maniscalco V

Abstract excerpt

The DNA damage-inducible SOS response of Escherichia coli includes an error-prone translesion DNA replication activity responsible for SOS mutagenesis. In certain recA mutant strains, in which the SOS response is expressed constitutively, SOS mutagenesis is manifested as a mutator activity. Like UV mutagenesis, SOS mutator activity requires the products of the umuDC operon and depends on RecA protein for at least...

Topics

Alleles
DNA Damage
DNA Repair
Escherichia coli
Mutation
Operon
Plasmids
Rec A Recombinases
SOS Response, Genetics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2188949
DOI: 10.1128/jb.172.6.3030-3036.1990
PMCID: PMC209104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2188949-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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RecA protein of Escherichia coli has a third essential role in SOS mutator activity.PMID 2188949Read ↗

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Mutations for Worse or Better: Low-Fidelity DNA Synthesis by SOS DNA Polymerase V Is a Tightly Regulated Double-Edged Sword.Semantic proximity Read ↗

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Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.Semantic proximity Read ↗

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