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Article

Specific amino acid changes enhance the anti-recombination activity of the UmuD'C complex.

Molecular microbiology - 1 Mar 2000

Sommer S, Coste G, Bailone A

Abstract excerpt

In addition to being an essential component of trans-lesion synthesis, the UmuD'C complex is an antagonist of RecA-mediated homologous recombination. When constitutively expressed at an elevated concentration, the UmuD'C complex sensitizes recA+ bacteria to DNA damage, whereas it has no effect on bacteria expressing a RecA [UmuR] protein that overcomes recombination inhibition. Using as a genetic screen enhanced...

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Identifiers

PMID: 10760145
DOI: 10.1046/j.1365-2958.2000.01809.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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